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    美国教授推荐书单《一生的读书计划》

    来源: 南方日报网络版     时间: 2019-05-26 20:38:20
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    恒】【瑞】【医】【药】【的】【业】【绩】【最】【突】【出】【的】【表】【现】【是】【“】【稳】【”】【。】【得】【益】【于】【创】【新】【成】【果】【的】【逐】【步】【收】【获】【以】【及】【现】【有】【产】【品】【逐】【步】【扩】【大】【市】【场】【,】【年】【恒】【瑞】【三】【大】【产】【品】【线】【保】【持】【稳】【步】【增】【长】【,】【其】【中】【肿】【瘤】【产】【品】【线】【增】【长】【.】【%】【,】【影】【像】【线】【产】【品】【销】【售】【额】【增】【长】【.】【%】【,】【麻】【醉】【线】【产】【品】【同】【比】【增】【长】【.】【%】【。】? 肿】【瘤】【药】【品】【仍】【然】【为】【恒】【瑞】【贡】【献】【了】【接】【近】【一】【半】【的】【收】【入】【,】【.】【亿】【元】【占】【总】【营】【收】【的】【%】【。】【此】【外】【,】【抗】【肿】【瘤】【产】【品】【线】【的】【毛】【利】【率】【为】【.】【%】【,】【高】【于】【影】【像】【产】【品】【线】【和】【麻】【醉】【产】【品】【线】【。】? 恒】【瑞】【在】【年】【报】【中】【披】【露】【了】【核】【心】【品】【种】【年】【医】【疗】【机】【构】【采】【购】【金】【额】【,】【共】【有】【个】【品】【种】【采】【购】【金】【额】【超】【过】【亿】【元】【:】【阿】【帕】【替】【尼】【.】【亿】【元】【,】【右】【美】【托】【咪】【定】【.】【亿】【元】【,】【多】【西】【他】【赛】【.】【亿】【元】【,】【碘】【克】【沙】【醇】【注】【射】【液】【亿】【元】【,】【吸】【入】【用】【七】【氟】【烷】【.】【亿】【元】【,】【注】【射】【用】【苯】【磺】【酸】【阿】【曲】【库】【铵】【.】【亿】【元】【。】? 作】【为】【恒】【瑞】【的】【第】【一】【个】【创】【新】【药】【产】【品】【,】【阿】【帕】【替】【尼】【还】【有】【很】【大】【的】【成】【长】【空】【间】【。】【恒】【瑞】【在】【年】【报】【电】【话】【会】【中】【披】【露】【:】【阿】【帕】【替】【尼】【肺】【癌】【适】【应】【症】【在】【做】【Ⅲ】【期】【,】【如】【果】【批】【准】【下】【来】【以】【后】【,】【会】【作】【为】【重】【点】【,】【还】【没】【有】【具】【体】【时】【间】【预】【期】【,】【至】【少】【下】【半】【年】【。】? 值】【得】【期】【待】【的】【是】【,】【年】【恒】【瑞】【有】【两】【个】【创】【新】【药】【获】【批】【上】【市】【,】【分】【别】【为】【硫】【培】【非】【格】【司】【亭】【注】【射】【液】【和】【吡】【咯】【替】【尼】【。】【恒】【瑞】【医】【药】【在】【财】【报】【电】【话】【会】【中】【表】【示】【:】【吡】【咯】【替】【尼】【、】【和】【白】【蛋】【白】【紫】【杉】【醇】【都】【是】【下】【半】【年】【开】【始】【卖】【,】【现】【在】【还】【不】【方】【便】【公】【布】【数】【据】【。】【但】【这】【两】【个】【大】【品】【种】【都】【被】【证】【券】【分】【析】【师】【认】【为】【有】【望】【进】【入】【亿】【元】【梯】【队】【。】? 根】【据】【天】【风】【证】【券】【的】【测】【算】【,】【中】【国】【升】【白】【药】【市】【场】【由】【大】【概】【亿】【元】【的】【规】【模】【,】【未】【来】【恒】【瑞】【、】【石】【药】【、】【齐】【鲁】【三】【家】【共】【同】【竞】【争】【这】【亿】【元】【市】【场】【,】【恒】【瑞】【的】【硫】【培】【非】【格】【司】【亭】【将】【来】【销】【售】【有】【望】【超】【过】【亿】【元】【。】【吡】【咯】【替】【尼】【获】【批】【适】【应】【症】【为】【表】【达】【阳】【性】【的】【晚】【期】【或】【转】【移】【性】【乳】【腺】【癌】【,】【目】【前】【还】【有】【多】【项】【临】【床】【试】【验】【在】【进】【行】【,】【未】【来】【成】【长】【空】【间】【巨】【大】【。】【预】【计】【该】【产】【品】【峰】【值】【销】【售】【预】【计】【超】【过】【亿】【元】【。】? 石】【药】【集】【团】【年】【年】【报】【中】【最】【亮】【眼】【的】【莫】【过】【于】【创】【新】【药】【的】【放】【量】【。】【全】【年】【创】【新】【药】【销】【售】【收】【入】【实】【现】【.】【亿】【港】【元】【(】【亿】【元】【)】【,】【同】【比】【增】【长】【.】【%】【,】【占】【总】【营】【收】【的】【%】【,】【接】【近】【一】【半】【。】【这】【也】【是】【石】【药】【集】【团】【多】【年】【前】【向】【创】【新】【药】【企】【转】【型】【之】【后】【,】【创】【新】【药】【业】【务】【收】【入】【首】【次】【超】【过】【百】【亿】【港】【元】【。】【此】【外】【,】【普】【药】【收】【入】【和】【原】【料】【药】【收】【入】【分】【别】【占】【总】【营】【收】【的】【.】【%】【、】【.】【%】【。】? 值】【得】【注】【意】【的】【是】【,】【石】【药】【集】【团】【将】【部】【分】【首】【仿】【药】【也】【划】【入】【“】【创】【新】【药】【”】【部】【分】【,】【如】【注】【射】【用】【白】【蛋】【白】【紫】【杉】【醇】【、】【甲】【磺】【酸】【伊】【马】【替】【尼】【等】【。】【短】【期】【内】【石】【药】【集】【团】【的】【业】【绩】【增】【长】【也】【主】【要】【靠】【这】【些】【产】【品】【带】【动】【。】? 作】【为】【石】【药】【集】【团】【第】【一】【个】【创】【新】【药】【产】【品】【,】【恩】【必】【普】【仍】【是】【石】【药】【集】【团】【业】【绩】【第】【一】【大】【驱】【动】【因】【素】【。】【年】【销】【售】【收】【入】【增】【长】【.】【%】【,】【预】【计】【销】【售】【额】【为】【.】【亿】【元】【,】【体】【量】【较】【大】【且】【仍】【在】【维】【持】【高】【速】【增】【长】【。】【恩】【必】【普】【销】【售】【增】【长】【的】【原】【因】【一】【方】【面】【是】【医】【保】【红】【利】【持】【续】【释】【放】【,】【另】【一】【方】【面】【,】【石】【药】【集】【团】【在】【年】【扩】【大】【了】【恩】【必】【普】【专】【线】【销】【售】【队】【伍】【,】【逐】【步】【开】【发】【县】【级】【和】【社】【区】【卫】【生】【服】【务】【中】【心】【等】【基】【层】【医】【疗】【市】【场】【,】【销】【售】【覆】【盖】【医】【院】【数】【目】【快】【速】【增】【加】【。】【石】【药】【在】【电】【话】【会】【中】【表】【示】【:】【相】【较】【全】【国】【的】【县】【级】【市】【场】【,】【公】【司】【目】【前】【拓】【展】【的】【恩】【必】【普】【市】【场】【还】【只】【是】【冰】【山】【一】【角】【,】【未】【来】【公】【司】【在】【空】【白】【市】【场】【的】【拓】【展】【和】【终】【端】【下】【沉】【将】【持】【续】【发】【力】【,】【保】【证】【产】【品】【持】【续】【的】【增】【长】【。】? 石】【药】【集】【团】【肿】【瘤】【药】【系】【列】【产】【品】【销】【售】【收】【入】【增】【长】【.】【%】【,】【是】【业】【绩】【第】【二】【大】【驱】【动】【因】【素】【。】【核】【心】【产】【品】【有】【多】【美】【素】【、】【津】【优】【力】【和】【年】【月】【获】【批】【上】【市】【的】【首】【仿】【药】【克】【艾】【力】【(】【注】【射】【用】【白】【蛋】【白】【紫】【杉】【醇】【)】【。】【石】【药】【集】【团】【在】【年】【扩】【大】【了】【津】【优】【力】【的】【销】【售】【队】【伍】【并】【增】【加】【了】【医】【院】【的】【覆】【盖】【,】【未】【来】【该】【产】【品】【的】【目】【标】【是】【成】【为】【中】【国】【长】【效】【市】【场】【的】【领】【导】【品】【牌】【。】【克】【艾】【力】【目】【前】【已】【经】【进】【入】【多】【省】【的】【大】【病】【医】【保】【目】【录】【,】【首】【年】【销】【售】【业】【绩】【亮】【眼】【,】【未】【来】【随】【着】【学】【术】【推】【广】【、】【更】【多】【适】【应】【症】【的】【获】【批】【,】【还】【将】【继】【续】【放】【量】【。】? 作】【为】【仿】【制】【药】【占】【据】【主】【要】【产】【品】【线】【,】【且】【贡】【献】【了】【大】【多】【数】【利】【润】【的】【当】【下】【,】【恒】【瑞】【医】【药】【、】【石】【药】【集】【团】【、】【中】【国】【生】【物】【制】【药】【都】【不】【可】【避】【免】【受】【到】【“】【+】【”】【影】【响】【。】? 由】【于】【错】【过】【“】【+】【”】【带】【量】【采】【购】【,】【恒】【瑞】【医】【药】【对】【超】【亿】【元】【大】【品】【种】【盐】【酸】【右】【美】【托】【咪】【定】【注】【射】【液】【主】【动】【下】【调】【价】【格】【。】【“】【+】【”】【之】【前】【,】【恒】【瑞】【的】【盐】【酸】【右】【美】【托】【咪】【定】【占】【据】【样】【本】【医】【院】【销】【量】【的】【%】【,】【是】【该】【市】【场】【的】【最】【大】【玩】【家】【,】【彼】【时】【扬】【子】【江】【的】【产】【品】【根】【本】【还】【未】【上】【市】【,】【却】【由】【于】【“】【+】【”】【的】【契】【机】【突】【然】【杀】【出】【来】【攫】【取】【恒】【瑞】【的】【市】【场】【份】【额】【。】【降】【价】【加】【上】【市】【场】【份】【额】【萎】【缩】【,】【恒】【瑞】【这】【款】【销】【量】【排】【名】【第】【三】【的】【大】【产】【品】【接】【下】【来】【一】【定】【会】【受】【影】【响】【。】? 让】【业】【界】【担】【心】【的】【还】【有】【未】【来】【注】【射】【剂】【的】【一】【致】【性】【评】【价】【以】【及】【带】【量】【采】【购】【。】【恒】【瑞】【医】【药】【在】【年】【年】【报】【电】【话】【会】【中】【表】【示】【:】【“】【注】【射】【剂】【一】【致】【性】【评】【价】【方】【案】【还】【没】【出】【来】【,】【但】【药】【监】【局】【已】【经】【在】【收】【集】【资】【料】【。】【如】【果】【注】【射】【剂】【也】【进】【行】【带】【量】【采】【购】【,】【业】【绩】【肯】【定】【会】【大】【幅】【下】【滑】【,】【如】【果】【发】【生】【会】【积】【极】【应】【对】【。】【”】? 恒】【瑞】【还】【提】【到】【,】【各】【地】【医】【保】【局】【成】【立】【之】【后】【,】【开】【展】【大】【范】【围】【的】【肿】【瘤】【药】【专】【项】【采】【购】【的】【可】【能】【性】【比】【较】【大】【,】【其】【产】【品】【价】【格】【会】【受】【到】【挑】【战】【,】【面】【临】【较】【大】【压】【力】【。】? 虽】【然】【仿】【制】【药】【集】【采】【政】【策】【正】【在】【落】【地】【,】【年】【恒】【瑞】【医】【药】【仍】【然】【扩】【充】【了】【销】【售】【队】【伍】【,】【销】【售】【人】【员】【增】【加】【接】【近】【人】【,】【累】【计】【销】【售】【人】【员】【达】【到】【人】【,】【销】【售】【费】【用】【也】【达】【到】【了】【新】【高】【,】【为】【.】【亿】【元】【,】【同】【比】【增】【加】【.】【%】【。】【对】【此】【,】【恒】【瑞】【表】【示】【:】【年】【扩】【充】【是】【为】【-】【上】【市】【人】【员】【储】【备】【;】【影】【像】【综】【合】【线】【也】【增】【加】【的】【比】【较】【大】【;】【带】【量】【采】【购】【以】【后】【,】【仿】【制】【药】【销】【售】【人】【员】【要】【压】【缩】【;】【销】【售】【人】【员】【不】【能】【再】【增】【加】【了】【,】【主】【要】【做】【内】【部】【整】【合】【。】? 石】【药】【集】【团】【款】【产】【品】【进】【入】【带】【量】【采】【购】【竞】【标】【之】【列】【,】【最】【终】【阿】【奇】【霉】【素】【、】【阿】【莫】【西】【林】【、】【曲】【马】【多】【在】【议】【价】【环】【节】【没】【能】【与】【谈】【判】【要】【求】【达】【成】【一】【致】【而】【流】【标】【。】【石】【药】【集】【团】【对】【外】【表】【示】【,】【四】【个】【产】【品】【销】【售】【总】【额】【全】【国】【范】【围】【内】【大】【概】【在】【亿】【左】【右】【,】【对】【集】【团】【整】【体】【销】【售】【贡】【献】【不】【大】【,】【暂】【时】【对】【集】【团】【业】【务】【和】【利】【润】【指】【标】【没】【有】【影】【响】【。】? “】【+】【”】【对】【石】【药】【集】【团】【的】【影】【响】【更】【多】【集】【中】【在】【其】【后】【续】【品】【种】【上】【。】【截】【至】【年】【底】【,】【石】【药】【集】【团】【过】【一】【致】【性】【评】【价】【的】【产】【品】【有】【个】【(】【品】【规】【)】【,】【还】【有】【个】【产】【品】【在】【一】【致】【性】【评】【价】【审】【评】【审】【批】【序】【列】【。】【通】【过】【评】【价】【的】【产】【品】【包】【括】【核】【心】【品】【种】【注】【射】【用】【白】【蛋】【白】【紫】【杉】【醇】【。】【石】【药】【集】【团】【在】【电】【话】【会】【中】【披】【露】【:】【白】【蛋】【白】【紫】【杉】【醇】【在】【第】【一】【稿】【集】【中】【采】【购】【文】【件】【中】【是】【有】【的】【,】【彼】【时】【公】【司】【股】【价】【跌】【了】【很】【多】【。】【这】【个】【品】【种】【不】【列】【入】【带】【量】【采】【购】【对】【我】【们】【是】【好】【事】【。】? 但】【随】【着】【带】【量】【采】【购】【继】【续】【推】【行】【,】【该】【产】【品】【仍】【不】【可】【避】【免】【地】【受】【到】【降】【价】【影】【响】【。】【不】【过】【石】【药】【集】【团】【也】【认】【为】【白】【蛋】【白】【紫】【杉】【醇】【上】【市】【不】【久】【,】【对】【公】【司】【业】【绩】【影】【响】【不】【大】【,】【市】【场】【的】【反】【应】【过】【激】【了】【。】【从】【石】【药】【集】【团】【目】【前】【的】【利】【润】【来】【源】【和】【仿】【制】【药】【营】【收】【规】【模】【来】【看】【,】【创】【新】【药】【和】【未】【来】【国】【际】【化】【是】【石】【药】【集】【团】【的】【发】【力】【重】【点】【。】? 中】【国】【生】【物】【制】【药】【在】【本】【次】【“】【+】【”】【带】【量】【采】【购】【中】【涉】【及】【到】【了】【个】【品】【种】【:】【瑞】【舒】【伐】【他】【汀】【、】【恩】【替】【卡】【韦】【、】【厄】【贝】【沙】【坦】【、】【替】【诺】【福】【韦】【二】【吡】【呋】【酯】【、】【伊】【马】【替】【尼】【、】【氟】【比】【洛】【芬】【。】【天】【风】【证】【券】【的】【数】【据】【显】【示】【,】【年】【前】【三】【季】【度】【个】【品】【种】【合】【计】【销】【售】【额】【亿】【元】【,】【占】【公】【司】【总】【营】【收】【的】【.】【%】【。】【尤】【其】【是】【销】【售】【规】【模】【超】【过】【亿】【元】【的】【大】【品】【种】【恩】【替】【卡】【韦】【。】【受】【此】【影】【响】【,】【中】【国】【生】【物】【制】【药】【的】【利】【润】【在】【年】【会】【被】【大】【大】【压】【缩】【。】【正】【大】【天】【晴】【相】【关】【人】【士】【此】【前】【曾】【在】【接】【受】【媒】【体】【采】【访】【时】【表】【示】【需】【要】【用】【别】【的】【产】【品】【来】【分】【摊】【原】【料】【、】【人】【工】【、】【流】【通】【等】【成】【本】【,】【才】【能】【保】【证】【该】【产】【品】【不】【亏】【本】【。】? 即】【使】【如】【此】【,】【由】【于】【中】【国】【生】【物】【制】【药】【创】【新】【药】【已】【经】【开】【始】【放】【量】【且】【产】【品】【较】【多】【、】【体】【量】【较】【大】【,】【中】【国】【生】【物】【制】【药】【表】【示】【仍】【然】【有】【底】【气】【保】【证】【每】【年】【%】【的】【研】【发】【投】【入】【不】【缩】【减】【,】【支】【持】【创】【新】【药】【研】【发】【进】【度】【。】? 随】【着】【仿】【制】【药】【进】【入】【微】【利】【时】【代】【,】【且】【创】【新】【药】【已】【经】【逐】【步】【成】【为】【恒】【瑞】【、】【石】【药】【、】【中】【国】【生】【物】【制】【药】【的】【主】【要】【利】【润】【来】【源】【,】【企】【业】【未】【来】【的】【潜】【力】【仍】【然】【是】【靠】【创】【新】【研】【发】【和】【产】【品】【管】【线】【。】【而】【研】【发】【方】【面】【的】【实】【力】【也】【是】【恒】【瑞】【医】【药】【最】【被】【看】【好】【的】【方】【面】【,】【是】【支】【撑】【其】【多】【倍】【市】【盈】【率】【的】【主】【要】【因】【素】【。】? 从】【研】【发】【投】【入】【来】【看】【,】【恒】【瑞】【医】【药】【仍】【处】【于】【龙】【头】【地】【位】【,】【中】【国】【生】【物】【制】【药】【研】【发】【投】【入】【在】【国】【内】【医】【药】【上】【市】【企】【业】【中】【排】【名】【第】【四】【,】【次】【于】【百】【济】【神】【州】【、】【恒】【瑞】【、】【复】【星】【,】【为】【.】【亿】【元】【。】【石】【药】【集】【团】【研】【发】【投】【入】【略】【低】【,】【为】【.】【亿】【元】【,】【占】【营】【收】【比】【重】【.】【%】【。】? 恒】【瑞】【医】【药】【年】【研】【发】【投】【入】【继】【续】【飙】【升】【。】【研】【发】【团】【队】【有】【多】【人】【,】【在】【中】【国】【、】【美】【国】【、】【日】【本】【等】【多】【地】【建】【有】【研】【发】【中】【心】【。】【年】【在】【-】【上】【的】【研】【发】【投】【入】【.】【亿】【元】【,】【比】【上】【年】【同】【比】【增】【加】【.】【%】【;】【贝】【伐】【珠】【单】【抗】【注】【射】【液】【研】【发】【投】【入】【.】【亿】【元】【,】【同】【比】【增】【加】【%】【;】【研】【发】【投】【入】【.】【亿】【元】【,】【同】【比】【增】【加】【%】【。】【报】【告】【期】【内】【,】【恒】【瑞】【医】【药】【取】【得】【创】【新】【药】【临】【床】【批】【件】【个】【,】【有】【个】【创】【新】【药】【正】【在】【临】【床】【开】【发】【。】?


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